4R11

A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo

4R11 の概要

• エントリーDOI: 10.2210/pdb4r11/pdb
• 関連するPDBエントリー: 4R0Z 4R10
• 分子名称: Protein humpback-2, Cadherin-related hmr-1, IODIDE ION, ... (4 entities in total)
• 機能のキーワード: armadillo repeat, cell adhesion, phosphorylation, cell adhesion-protein binding complex, cell adhesion/protein binding
• 由来する生物種: Caenorhabditis elegans (roundworm); 詳細
• 細胞内の位置: Cell junction, adherens junction : O44326; Cell membrane ; Single-pass type I membrane protein : Q967F4
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 216583.03

構造登録者

Choi, H.-J.,Loveless, T.,Lynch, A.,Bang, I.,Hardin, J.,Weis, W.I. (登録日: 2014-08-03, 公開日: 2015-04-29)

• 主引用文献: Choi, H.J.,Loveless, T.,Lynch, A.M.,Bang, I.,Hardin, J.,Weis, W.I.; A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo; Dev.Cell, 33:82-93, 2015; PubMed: 25850673; DOI: 10.1016/j.devcel.2015.02.005

実験手法

X-RAY DIFFRACTION (2.789 Å)