4QXG

Antigen binding fragment of an anti IFNAR1 antibody

Summary for 4QXG

• Entry DOI: 10.2210/pdb4qxg/pdb
• Descriptor: Fab, heavy chain, IgG1, Fab, light chain, IgG1, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: igv and igc type folds, antigen binding, ifnar1, interferon alpha receptor 1, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47243.67

Authors

Oganesyan, V.Y.,Dall'Acqua, W.F. (deposition date: 2014-07-20, release date: 2015-02-25, Last modification date: 2015-04-22)

• Primary citation: Peng, L.,Oganesyan, V.,Wu, H.,Dall'Acqua, W.F.,Damschroder, M.M.; Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-alpha receptor 1 antibody.; MAbs, 7:428-439, 2015; PubMed: 25606664; DOI: 10.1080/19420862.2015.1007810

Experimental method

X-RAY DIFFRACTION (2.3 Å)