4QVE
Crystal structure of Bcl-xL in complex with BID BH3 domain
Summary for 4QVE
Entry DOI | 10.2210/pdb4qve/pdb |
Related | 1MAZ 4QVF |
Descriptor | Bcl-2-like protein 1, Peptide from BH3-interacting domain death agonist, IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | protein-peptide complex, bcl-2 like, heterodimer, apoptosis, anti-apoptotic, bh3 binding, bid bh3 |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 Cytoplasm . BH3-interacting domain death agonist p15: Mitochondrion membrane . BH3-interacting domain death agonist p13: Mitochondrion membrane . Isoform 1: Cytoplasm. Isoform 3: Cytoplasm. Isoform 2: Mitochondrion membrane: P55957 |
Total number of polymer chains | 2 |
Total formula weight | 23075.41 |
Authors | Sreekanth, R.,Yoon, H.S. (deposition date: 2014-07-14, release date: 2015-06-10, Last modification date: 2023-11-08) |
Primary citation | Rajan, S.,Choi, M.,Baek, K.,Yoon, H.S. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis. Proteins, 83:1262-1272, 2015 Cited by PubMed: 25907960DOI: 10.1002/prot.24816 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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