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4QV0

yCP beta5-A49T-A50V-double mutant

Summary for 4QV0
Entry DOI10.2210/pdb4qv0/pdb
Related1RYP 4QTR 4QUX 4QV0 4QV1 4QV3 4QV4 4QV5 4QV6 4QV7 4QV8 4QV9 4QVL 4QVM 4QVN 4QVP 4QVQ
DescriptorProteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (17 entities in total)
Functional Keywordscancer, proteasome, bortezomib, drug resistance, binding analysis, hydrolase
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
More
Total number of polymer chains28
Total formula weight731383.67
Authors
Huber, E.M.,Heinemeyer, W.,Groll, M. (deposition date: 2014-07-14, release date: 2015-02-04, Last modification date: 2023-09-20)
Primary citationHuber, E.M.,Heinemeyer, W.,Groll, M.
Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23:407-417, 2015
Cited by
PubMed: 25599643
DOI: 10.1016/j.str.2014.11.019
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

217705

数据于2024-03-27公开中

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