4QUT
Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) complexed with Histone H4-K(ac)12
Summary for 4QUT
Entry DOI | 10.2210/pdb4qut/pdb |
Related | 4QUU |
Descriptor | ATPase family AAA domain-containing protein 2, Histone H4, SULFATE ION, ... (5 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, signaling protein, bromodomain, actyl-lysine binding, atpase family aaa domain-containing protein 2, epigenetics, histone, bromodomain-histone, structural genomics consortium (sgc) |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q6PL18 P62805 |
Total number of polymer chains | 2 |
Total formula weight | 16996.17 |
Authors | Chaikuad, A.,Felletar, I.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-07-12, release date: 2014-07-30, Last modification date: 2023-12-06) |
Primary citation | Morozumi, Y.,Boussouar, F.,Tan, M.,Chaikuad, A.,Jamshidikia, M.,Colak, G.,He, H.,Nie, L.,Petosa, C.,de Dieuleveult, M.,Curtet, S.,Vitte, A.L.,Rabatel, C.,Debernardi, A.,Cosset, F.L.,Verhoeyen, E.,Emadali, A.,Schweifer, N.,Gianni, D.,Gut, M.,Guardiola, P.,Rousseaux, S.,Gerard, M.,Knapp, S.,Zhao, Y.,Khochbin, S. Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells. J Mol Cell Biol, 8:349-362, 2016 Cited by PubMed: 26459632DOI: 10.1093/jmcb/mjv060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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