4QUH

Caspase-3 T140G

Summary for 4QUH

Entry DOI	10.2210/pdb4quh/pdb
Related PRD ID	PRD_000238
Descriptor	Caspase-3, short peptde, ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, ... (7 entities in total)
Functional Keywords	allosteric network, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P42574
Total number of polymer chains	5
Total formula weight	65363.80
Authors	Cade, C.,Swartz, P.D.,MacKenzie, S.H.,Clark, A.C. (deposition date: 2014-07-10, release date: 2014-11-05, Last modification date: 2017-11-22)
Primary citation	Cade, C.,Swartz, P.,MacKenzie, S.H.,Clark, A.C. Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53:7582-7595, 2014 Cited by PubMed: 25343534 DOI: 10.1021/bi500874k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.759 Å)

Structure validation