4QRA

Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation

4QRA の概要

• エントリーDOI: 10.2210/pdb4qra/pdb
• 関連するPDBエントリー: 4QR7 4QRB
• 分子名称: L,d-transpeptidase LdtB, CALCIUM ION (3 entities in total)
• 機能のキーワード: structural genomics, enzyme function initiative, center for structural genomics of infectious diseases, csgid, l-d-transpeptidase; d-d-transpeptidase; single anomalous diffraction; imipenem; meropenem;, hydrolase
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cell membrane ; Lipid-anchor : I6Y9J2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75397.77

構造登録者

Gokulan, K.,Varughese, K.I. (登録日: 2014-06-30, 公開日: 2015-12-23, 最終更新日: 2024-02-28)

• 主引用文献: Gokulan, K.,Khare, S.,Cerniglia, C.E.,Foley, S.L.,Varughese, K.I.; Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation; To be Published,

実験手法

X-RAY DIFFRACTION (2.29 Å)