4QR7
Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation
4QR7 の概要
エントリーDOI | 10.2210/pdb4qr7/pdb |
関連するPDBエントリー | 4QRA 4QRB |
分子名称 | L,d-transpeptidase LdtB, GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA, (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, ... (4 entities in total) |
機能のキーワード | structural genomics, enzyme function initiative, center for structural genomics of infectious diseases, csgid, l-d-transpeptidase; d-d-transpeptidase; single anomalous diffraction; imipenem; meropenem; peptidoglycan; beta-lactamase, hydrolase |
由来する生物種 | Mycobacterium tuberculosis |
細胞内の位置 | Cell membrane ; Lipid-anchor : I6Y9J2 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 38986.22 |
構造登録者 | |
主引用文献 | Gokulan, K.,Khare, S.,Cerniglia, C.E.,Foley, S.L.,Varughese, K.I. Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation To be Published, |
実験手法 | X-RAY DIFFRACTION (2.303 Å) |
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