4QQK

Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) with GMS

Summary for 4QQK

Entry DOI	10.2210/pdb4qqk/pdb
Descriptor	Protein arginine N-methyltransferase 6, (5S)-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}-N~6~-carbamimidoyl-L-lysine, GLYCEROL, ... (5 entities in total)
Functional Keywords	hrmt1l6, protein arginine n-methyltransferase 6, structural genomics, structural genomics consortium, sgc, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q96LA8
Total number of polymer chains	1
Total formula weight	42604.11
Authors	Dong, A.,Zeng, H.,He, H.,Wernimont, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Min, J.,Luo, M.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2014-06-27, release date: 2014-07-16, Last modification date: 2023-09-20)
Primary citation	Wu, H.,Zheng, W.,Eram, M.S.,Vhuiyan, M.,Dong, A.,Zeng, H.,He, H.,Brown, P.,Frankel, A.,Vedadi, M.,Luo, M.,Min, J. Structural basis of arginine asymmetrical dimethylation by PRMT6. Biochem. J., 473:3049-3063, 2016 Cited by PubMed: 27480107 DOI: 10.1042/BCJ20160537 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation