4QQK

Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) with GMS

4QQK の概要

• エントリーDOI: 10.2210/pdb4qqk/pdb
• 分子名称: Protein arginine N-methyltransferase 6, (5S)-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}-N~6~-carbamimidoyl-L-lysine, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: hrmt1l6, protein arginine n-methyltransferase 6, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : Q96LA8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42604.11

構造登録者

Dong, A.,Zeng, H.,He, H.,Wernimont, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Min, J.,Luo, M.,Wu, H.,Structural Genomics Consortium (SGC) (登録日: 2014-06-27, 公開日: 2014-07-16, 最終更新日: 2023-09-20)

• 主引用文献: Wu, H.,Zheng, W.,Eram, M.S.,Vhuiyan, M.,Dong, A.,Zeng, H.,He, H.,Brown, P.,Frankel, A.,Vedadi, M.,Luo, M.,Min, J.; Structural basis of arginine asymmetrical dimethylation by PRMT6.; Biochem. J., 473:3049-3063, 2016; PubMed: 27480107; DOI: 10.1042/BCJ20160537

実験手法

X-RAY DIFFRACTION (1.88 Å)