4QN0

Crystal structure of the CPS-6 mutant Q130K

Summary for 4QN0

Entry DOI	10.2210/pdb4qn0/pdb
Related	3S5B
Descriptor	Endonuclease G, mitochondrial, MAGNESIUM ION (3 entities in total)
Functional Keywords	beta-beta-alpha metal motif, endoribonuclease, mitochondrial membrane, hydrolase
Biological source	Caenorhabditis elegans (roundworm)
Cellular location	Mitochondrion : Q95NM6
Total number of polymer chains	4
Total formula weight	109686.56
Authors	Lin, J.L.J.,Yuan, H.S. (deposition date: 2014-06-17, release date: 2015-06-17, Last modification date: 2023-11-08)
Primary citation	Lin, J.L.J.,Nakagawa, A.,Skeen-Gaar, R.,Yang, W.Z.,Zhao, P.,Zhang, Z.,Ge, X.,Mitani, S.,Xue, D.,Yuan, H.S. Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G Cell Rep, 16:279-287, 2016 Cited by PubMed: 27346342 DOI: 10.1016/j.celrep.2016.05.090 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.74 Å)

Structure validation