Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4QKZ

X-ray structure of the catalytic domain of MMP-8 with the inhibitor ML115

Summary for 4QKZ
Entry DOI10.2210/pdb4qkz/pdb
DescriptorNeutrophil collagenase, CALCIUM ION, ZINC ION, ... (6 entities in total)
Functional Keywordshydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasmic granule: P22894
Total number of polymer chains1
Total formula weight18925.23
Authors
Pochetti, G.,Montanari, R.,Capelli, D.,Tortorella, P. (deposition date: 2014-06-10, release date: 2015-06-17, Last modification date: 2023-11-08)
Primary citationLaghezza, A.,Piemontese, L.,Brunetti, L.,Caradonna, A.,Agamennone, M.,Di Pizio, A.,Pochetti, G.,Montanari, R.,Capelli, D.,Tauro, M.,Loiodice, F.,Tortorella, P.
Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy.
Pharmaceuticals, 13:-, 2020
Cited by
PubMed: 32492898
DOI: 10.3390/ph13060113
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.2 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon