4QKL

Influenza A M2 wild type TM domain at high pH in the lipidic cubic phase under room temperature diffraction conditions

Summary for 4QKL

Entry DOI	10.2210/pdb4qkl/pdb
Related	4QK6 4QK7 4QKC 4QKM
Descriptor	influenza M2 monomer, TM domain (22-46), CHLORIDE ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	transmembrane alpha helix, ph-activated proton channel, viral protein
Biological source	Influenza A virus
Cellular location	Virion membrane : W8PGZ1
Total number of polymer chains	1
Total formula weight	2932.02
Authors	Thomaston, J.L.,DeGrado, W.F. (deposition date: 2014-06-06, release date: 2015-11-11, Last modification date: 2023-09-20)
Primary citation	Thomaston, J.L.,Alfonso-Prieto, M.,Woldeyes, R.A.,Fraser, J.S.,Klein, M.L.,Fiorin, G.,DeGrado, W.F. High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction. Proc.Natl.Acad.Sci.USA, 112:14260-14265, 2015 Cited by PubMed: 26578770 DOI: 10.1073/pnas.1518493112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.711 Å)

Structure validation