4QJ1
Co-crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from Cryptosporidium parvum with inhibitor N109
Summary for 4QJ1
Entry DOI | 10.2210/pdb4qj1/pdb |
Related | 3FFS 4IXH |
Descriptor | Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-(4-chloro-3-methoxyphenyl)-2-(4-oxochromeno[4,3-c]pyrazol-1(4H)-yl)acetamide, ... (7 entities in total) |
Functional Keywords | structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, alpha-beta fold, tim barrel, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Cryptosporidium parvum More |
Cellular location | Cytoplasm : Q8T6T2 |
Total number of polymer chains | 4 |
Total formula weight | 157245.95 |
Authors | Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-06-03, release date: 2014-08-06, Last modification date: 2023-09-20) |
Primary citation | Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A. Co-crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from Cryptosporidium parvum with inhibitor N109 To be Published, |
Experimental method | X-RAY DIFFRACTION (2.415 Å) |
Structure validation
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