4QJ1

Co-crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from Cryptosporidium parvum with inhibitor N109

4QJ1 の概要

• エントリーDOI: 10.2210/pdb4qj1/pdb
• 関連するPDBエントリー: 3FFS 4IXH
• 分子名称: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-(4-chloro-3-methoxyphenyl)-2-(4-oxochromeno[4,3-c]pyrazol-1(4H)-yl)acetamide, ... (7 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, alpha-beta fold, tim barrel, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Cryptosporidium parvum; 詳細
• 細胞内の位置: Cytoplasm : Q8T6T2
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 157245.95

構造登録者

Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2014-06-03, 公開日: 2014-08-06, 最終更新日: 2023-09-20)

• 主引用文献: Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.; Co-crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from Cryptosporidium parvum with inhibitor N109; To be Published,

実験手法

X-RAY DIFFRACTION (2.415 Å)