4QAC
X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(4-methylpiperidin-1-yl)-6-(4-(trifluoromethyl)phenyl)pyrimidin-2-amine
Summary for 4QAC
| Entry DOI | 10.2210/pdb4qac/pdb |
| Related | 1UV6 1UW6 1UX2 4QAA 4QAB |
| Descriptor | Acetylcholine-binding protein, PHOSPHATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | acetylcholine-binding protein |
| Biological source | Lymnaea stagnalis (Great pond snail) |
| Cellular location | Secreted: P58154 |
| Total number of polymer chains | 10 |
| Total formula weight | 253767.51 |
| Authors | Kaczanowska, K.,Harel, M.,Radic, Z.,Changeux, J.-P.,Finn, M.G.,Taylor, P. (deposition date: 2014-05-03, release date: 2014-07-16, Last modification date: 2020-07-29) |
| Primary citation | Kaczanowska, K.,Harel, M.,Radic, Z.,Changeux, J.P.,Finn, M.G.,Taylor, P. Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein. Proc.Natl.Acad.Sci.USA, 111:10749-10754, 2014 Cited by PubMed: 25006260DOI: 10.1073/pnas.1410992111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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