4QAB

X-RAY STRUCTURE of ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(MORPHOLIN-4-YL)-6-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE

4QAB の概要

• エントリーDOI: 10.2210/pdb4qab/pdb
• 関連するPDBエントリー: 1UV6 1UW6 1UX2 4QAA 4QAC
• 分子名称: Acetylcholine-binding protein, 4-(morpholin-4-yl)-6-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: acetylcholine-binding protein
• 由来する生物種: Lymnaea stagnalis (Great pond snail)
• 細胞内の位置: Secreted: P58154
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 253646.97

構造登録者

Kaczanowska, K.,Harel, M.,Radic, Z.,Changeux, J.-P.,Finn, M.G.,Taylor, P. (登録日: 2014-05-03, 公開日: 2014-07-16, 最終更新日: 2020-07-29)

• 主引用文献: Kaczanowska, K.,Harel, M.,Radic, Z.,Changeux, J.P.,Finn, M.G.,Taylor, P.; Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein.; Proc.Natl.Acad.Sci.USA, 111:10749-10754, 2014; PubMed: 25006260; DOI: 10.1073/pnas.1410992111

実験手法

X-RAY DIFFRACTION (2.984 Å)