4Q8F
Human DNA polymerase eta extending primer immediately after a phenanthriplatin adducted G
Summary for 4Q8F
Entry DOI | 10.2210/pdb4q8f/pdb |
Related | 4Q8E |
Descriptor | DNA polymerase eta, 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', ... (7 entities in total) |
Functional Keywords | polymerase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9Y253 |
Total number of polymer chains | 3 |
Total formula weight | 56121.15 |
Authors | Gregory, M.T.,Yang, W. (deposition date: 2014-04-26, release date: 2014-07-02, Last modification date: 2024-02-28) |
Primary citation | Gregory, M.T.,Park, G.Y.,Johnstone, T.C.,Lee, Y.S.,Yang, W.,Lippard, S.J. Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage. Proc.Natl.Acad.Sci.USA, 111:9133-9138, 2014 Cited by PubMed: 24927576DOI: 10.1073/pnas.1405739111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.797 Å) |
Structure validation
Download full validation report