4Q5H
Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate
Summary for 4Q5H
Entry DOI | 10.2210/pdb4q5h/pdb |
Related | 4QSE |
Descriptor | Protein kinase OspG, Polyubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (6 entities in total) |
Functional Keywords | protein-protein complex, structural genomics, montreal-kingston bacterial structural genomics initiative, bsgi, kinase fold, inhibition of nf-kb pathway, unknown function, protein binding |
Biological source | Shigella sonnei More |
Cellular location | Secreted : Q3YTH2 Cytoplasm : P0CG63 Nucleus : P68036 |
Total number of polymer chains | 3 |
Total formula weight | 47342.58 |
Authors | Cygler, M.,Grishin, A.M.,Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (deposition date: 2014-04-16, release date: 2014-07-02, Last modification date: 2023-09-20) |
Primary citation | Grishin, A.M.,Condos, T.E.,Barber, K.R.,Campbell-Valois, F.X.,Parsot, C.,Shaw, G.S.,Cygler, M. Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22:878-888, 2014 Cited by PubMed: 24856362DOI: 10.1016/j.str.2014.04.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.999 Å) |
Structure validation
Download full validation report