4Q02
Second-site screening of K-Ras in the presence of covalently attached first-site ligands
Summary for 4Q02
Entry DOI | 10.2210/pdb4q02/pdb |
Related | 4PZY 4PZZ 4Q01 4Q03 |
Descriptor | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | small gtpase, signaling transduction, sos, raf, cytosol, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01116 |
Total number of polymer chains | 1 |
Total formula weight | 19984.56 |
Authors | Sun, Q.,Phan, J.,Friberg, A.,Camper, D.V.,Olejniczak, E.T.,Fesik, S.W. (deposition date: 2014-03-31, release date: 2014-09-10) |
Primary citation | Sun, Q.,Phan, J.,Friberg, A.R.,Camper, D.V.,Olejniczak, E.T.,Fesik, S.W. A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand. J.Biomol.Nmr, 60:11-14, 2014 Cited by PubMed: 25087006DOI: 10.1007/s10858-014-9849-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.702 Å) |
Structure validation
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