4PZF

Berberine bridge enzyme G164A variant, a reticuline dehydrogenase

4PZF の概要

• エントリーDOI: 10.2210/pdb4pzf/pdb
• 関連するPDBエントリー: 3D2H 4PVE 4PVH 4PVJ 4PVK 4PWB 4PWC
• 分子名称: Reticuline oxidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total)
• 機能のキーワード: flavoprotein, bi-covalent flavinylation, oxidoreductase, reticuline oxidase, berberine bridge-forming enzyme, tetrahydroprotoberberine synthase
• 由来する生物種: Eschscholzia californica (California poppy)
• 細胞内の位置: Cytoplasmic vesicle: P30986
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 247542.27

構造登録者

Zafred, D.,Wallner, S.,Steiner, B.,Macheroux, P. (登録日: 2014-03-30, 公開日: 2014-04-23, 最終更新日: 2023-09-20)

• 主引用文献: Zafred, D.,Steiner, B.,Teufelberger, A.R.,Hromic, A.,Karplus, P.A.,Schofield, C.J.,Wallner, S.,Macheroux, P.; Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction.; Febs J., 282:3060-3074, 2015; PubMed: 25619330; DOI: 10.1111/febs.13212

実験手法

X-RAY DIFFRACTION (2.2 Å)