4PXF
Crystal structure of the active G-protein-coupled receptor opsin in complex with the finger-loop peptide derived from the full-length arrestin-1
Summary for 4PXF
Entry DOI | 10.2210/pdb4pxf/pdb |
Related PRD ID | PRD_900006 |
Descriptor | Rhodopsin, S-arrestin, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | retinal protein, photoreceptor, g-protein coupled receptor, phosphoprotein, photoreceptor protein, sensory transduction, transducer, transmembrane, vision, signaling protein, visual arrestin, desensitisation of the visual transduction cascade, binding to acticated and phosphorylated rhodopsin, rhodopsin, opsin |
Biological source | Bos taurus (Bovine) More |
Cellular location | Membrane; Multi-pass membrane protein: P02699 |
Total number of polymer chains | 2 |
Total formula weight | 42650.43 |
Authors | Szczepek, M.,Scheerer, P. (deposition date: 2014-03-23, release date: 2014-09-17, Last modification date: 2023-09-20) |
Primary citation | Szczepek, M.,Beyriere, F.,Hofmann, K.P.,Elgeti, M.,Kazmin, R.,Rose, A.,Bartl, F.J.,von Stetten, D.,Heck, M.,Sommer, M.E.,Hildebrand, P.W.,Scheerer, P. Crystal structure of a common GPCR-binding interface for G protein and arrestin. Nat Commun, 5:4801-4801, 2014 Cited by PubMed: 25205354DOI: 10.1038/ncomms5801 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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