4PXF
Crystal structure of the active G-protein-coupled receptor opsin in complex with the finger-loop peptide derived from the full-length arrestin-1
4PXF の概要
エントリーDOI | 10.2210/pdb4pxf/pdb |
関連するBIRD辞書のPRD_ID | PRD_900006 |
分子名称 | Rhodopsin, S-arrestin, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
機能のキーワード | retinal protein, photoreceptor, g-protein coupled receptor, phosphoprotein, photoreceptor protein, sensory transduction, transducer, transmembrane, vision, signaling protein, visual arrestin, desensitisation of the visual transduction cascade, binding to acticated and phosphorylated rhodopsin, rhodopsin, opsin |
由来する生物種 | Bos taurus (Bovine) 詳細 |
細胞内の位置 | Membrane; Multi-pass membrane protein: P02699 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 42650.43 |
構造登録者 | |
主引用文献 | Szczepek, M.,Beyriere, F.,Hofmann, K.P.,Elgeti, M.,Kazmin, R.,Rose, A.,Bartl, F.J.,von Stetten, D.,Heck, M.,Sommer, M.E.,Hildebrand, P.W.,Scheerer, P. Crystal structure of a common GPCR-binding interface for G protein and arrestin. Nat Commun, 5:4801-4801, 2014 Cited by PubMed: 25205354DOI: 10.1038/ncomms5801 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.75 Å) |
構造検証レポート
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