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4PW6

structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex II

Summary for 4PW6
Entry DOI10.2210/pdb4pw6/pdb
Related4PW5
DescriptorE3 ubiquitin-protein ligase UHRF2, 5hmC-containing DNA1, 5hmC-containing DNA2 (3 entities in total)
Functional Keywordssra, 5hmc binding, 5hmc-containing dna, hydroxymethylation, nuclear, ligase-dna complex, ligase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: Q96PU4
Total number of polymer chains4
Total formula weight58513.34
Authors
Zhou, T.,Xiong, J.,Wang, M.,Yang, N.,Wong, J.,Zhu, B.,Xu, R.M. (deposition date: 2014-03-18, release date: 2014-05-07, Last modification date: 2023-09-20)
Primary citationZhou, T.,Xiong, J.,Wang, M.,Yang, N.,Wong, J.,Zhu, B.,Xu, R.M.
Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
Mol.Cell, 54:879-886, 2014
Cited by
PubMed: 24813944
DOI: 10.1016/j.molcel.2014.04.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.789 Å)
Structure validation

217705

数据于2024-03-27公开中

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