4PW5

structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex I

Summary for 4PW5

• Entry DOI: 10.2210/pdb4pw5/pdb
• Related: 4PW6 4PW7
• Descriptor: E3 ubiquitin-protein ligase UHRF2, 5hmC-containing DNA1, 5hmC-containing DNA2, ... (4 entities in total)
• Functional Keywords: sra, 5hmc binding, 5hmc-containing dna, hydroxymethylation, nuclear, ligase-dna complex, ligase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q96PU4
• Total number of polymer chains: 8
• Total formula weight: 116952.56

Authors

ZHou, T.,Xiong, J.,Wang, M.,Yang, N.,Wong, J.,Zhu, B.,Xu, R.M. (deposition date: 2014-03-18, release date: 2014-05-07, Last modification date: 2023-09-20)

• Primary citation: Zhou, T.,Xiong, J.,Wang, M.,Yang, N.,Wong, J.,Zhu, B.,Xu, R.M.; Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.; Mol.Cell, 54:879-886, 2014; PubMed: 24813944; DOI: 10.1016/j.molcel.2014.04.003

Experimental method

X-RAY DIFFRACTION (2.204 Å)