4PW2

Crystal structure of D-glucuronyl C5 epimerase

Summary for 4PW2

DescriptorD-glucuronyl C5 epimerase B, CITRIC ACID (3 entities in total)
Functional Keywordsepimerization enzyme, multiple domain structure, heparan sulfate c5-epimerase, heparin, heparan sulfate, isomerase
Biological sourceDanio rerio (leopard danio,zebra danio,zebra fish)
Total number of polymer chains1
Total molecular weight66328.31
Authors
Ke, J.,Qin, Y.,Gu, X.,Brunzelle, J.S.,Xu, H.E.,Ding, K. (deposition date: 2014-03-18, release date: 2015-01-14, Last modification date: 2015-03-18)
Primary citation
Qin, Y.,Ke, J.,Gu, X.,Fang, J.,Wang, W.,Cong, Q.,Li, J.,Tan, J.,Brunzelle, J.S.,Zhang, C.,Jiang, Y.,Melcher, K.,Li, J.P.,Xu, H.E.,Ding, K.
Structural and Functional Study of d-Glucuronyl C5-epimerase.
J.Biol.Chem., 290:4620-4630, 2015
PubMed: 25568314 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M114.602201
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.237401.4%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution