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4PVG

Crystal structure of protein tyrosine phosphatase Shp2 catalytic domain complex with small molecular compound L88N79

Summary for 4PVG
Entry DOI10.2210/pdb4pvg/pdb
DescriptorTyrosine-protein phosphatase non-receptor type 11, 2-[3-({4-[(1,3-benzodioxol-5-ylmethyl)amino]-4-oxobutanoyl}amino)phenyl]-6-hydroxy-3-iodo-1-methyl-1H-indole-5-carboxylic acid (3 entities in total)
Functional Keywordshydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q06124
Total number of polymer chains1
Total formula weight35619.10
Authors
Zhang, Z.-Y.,Zeng, L.,Liu, D.,Yu, Z. (deposition date: 2014-03-17, release date: 2015-04-15, Last modification date: 2023-09-20)
Primary citationZhang, Z.-Y.,Zeng, L.,Liu, D.,Yu, Z.
Crystal structure of protein tyrosine Shp2 catalytic domain complex with compound L88N79
To be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

数据于2024-03-27公开中

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