4PTH
Ensemble model for Escherichia coli dihydrofolate reductase at 100K
Summary for 4PTH
Entry DOI | 10.2210/pdb4pth/pdb |
Related | 4PSS 4PSY 4PTJ |
Descriptor | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | rossmann fold, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 19346.02 |
Authors | Keedy, D.A.,van den Bedem, H.,Sivak, D.A.,Petsko, G.A.,Ringe, D.,Wilson, M.A.,Fraser, J.S. (deposition date: 2014-03-10, release date: 2014-05-14, Last modification date: 2023-09-20) |
Primary citation | Keedy, D.A.,van den Bedem, H.,Sivak, D.A.,Petsko, G.A.,Ringe, D.,Wilson, M.A.,Fraser, J.S. Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR. Structure, 22:899-910, 2014 Cited by PubMed: 24882744DOI: 10.1016/j.str.2014.04.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.85 Å) |
Structure validation
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