4PPR

Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem

4PPR の概要

• エントリーDOI: 10.2210/pdb4ppr/pdb
• 関連するPDBエントリー: 4P0M
• 分子名称: Penicillin-binding protein DacB1, (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid (3 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, tb structural genomics consortium, tbsgc, penicillin-binding protein, peptidoglycan d, d-peptidase, hydrolase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35100.28

構造登録者

Prigozhin, D.M.,Huizar, J.P.,Mavrici, D.,Alber, T.,TB Structural Genomics Consortium (TBSGC) (登録日: 2014-02-27, 公開日: 2014-11-05, 最終更新日: 2023-09-20)

• 主引用文献: Prigozhin, D.M.,Krieger, I.V.,Huizar, J.P.,Mavrici, D.,Waldo, G.S.,Hung, L.W.,Sacchettini, J.C.,Terwilliger, T.C.,Alber, T.; Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.; Plos One, 9:e116249-e116249, 2014; PubMed: 25551456; DOI: 10.1371/journal.pone.0116249

実験手法

X-RAY DIFFRACTION (2 Å)