4PPI

Crystal structure of Bcl-xL hexamer

Summary for 4PPI

• Entry DOI: 10.2210/pdb4ppi/pdb
• Descriptor: Bcl-2-like protein 1, GLYCEROL (3 entities in total)
• Functional Keywords: 3d domain swap, apoptosis, anti-apoptotic, bcl-2 family
• Biological source: Homo sapiens (human)
• Cellular location: Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817
• Total number of polymer chains: 1
• Total formula weight: 19405.31

Authors

Sreekanth, R.,Yoon, H.S. (deposition date: 2014-02-27, release date: 2015-03-04, Last modification date: 2023-11-08)

• Primary citation: Rajan, S.,Choi, M.,Nguyen, Q.T.,Ye, H.,Liu, W.,Toh, H.T.,Kang, C.,Kamariah, N.,Li, C.,Huang, H.,White, C.,Baek, K.,Gruber, G.,Yoon, H.S.; Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport; Sci Rep, 5:10609-10609, 2015; PubMed: 26023881; DOI: 10.1038/srep10609

Experimental method

X-RAY DIFFRACTION (2.851 Å)