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4PP6

Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Resveratrol

Summary for 4PP6
Entry DOI10.2210/pdb4pp6/pdb
Related4PPP 4PPS
DescriptorEstrogen receptor, Nuclear receptor coactivator 2, RESVERATROL, ... (4 entities in total)
Functional Keywordsnuclear hormone receptor, transcription factor, ligand binding, nucleus, protein binding
Biological sourceHomo sapiens (human)
More
Cellular locationIsoform 1: Nucleus. Isoform 3: Nucleus. Nucleus: P03372
Nucleus: Q15596
Total number of polymer chains4
Total formula weight58398.82
Authors
Primary citationNwachukwu, J.C.,Srinivasan, S.,Bruno, N.E.,Parent, A.A.,Hughes, T.S.,Pollock, J.A.,Gjyshi, O.,Cavett, V.,Nowak, J.,Garcia-Ordonez, R.D.,Houtman, R.,Griffin, P.R.,Kojetin, D.J.,Katzenellenbogen, J.A.,Conkright, M.D.,Nettles, K.W.
Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3:e02057-e02057, 2014
Cited by
PubMed: 24771768
DOI: 10.7554/eLife.02057
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.201 Å)
Structure validation

217705

數據於2024-03-27公開中

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