4PLN

Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5)

Summary for 4PLN

• Entry DOI: 10.2210/pdb4pln/pdb
• Related: 4PLM 4PLO
• Descriptor: Netrin-1, Neogenin, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: elongated, cysteine rich, glycoprotein, complex, protein binding
• Biological source: Gallus gallus (Chicken); More
• Total number of polymer chains: 4
• Total formula weight: 144014.22

Authors

Xu, K.,Nikolov, D.B. (deposition date: 2014-05-18, release date: 2014-06-18, Last modification date: 2023-12-27)

• Primary citation: Xu, K.,Wu, Z.,Renier, N.,Antipenko, A.,Tzvetkova-Robev, D.,Xu, Y.,Minchenko, M.,Nardi-Dei, V.,Rajashankar, K.R.,Himanen, J.,Tessier-Lavigne, M.,Nikolov, D.B.; Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.; Science, 344:1275-1279, 2014; PubMed: 24876346; DOI: 10.1126/science.1255149

Experimental method

X-RAY DIFFRACTION (3.2 Å)