4PJW
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES
Summary for 4PJW
Entry DOI | 10.2210/pdb4pjw/pdb |
Related | 4PJU |
Descriptor | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | sister chromatid cohesion, cohesin subunits, protein-protein interaction, heat repeat, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 131871.44 |
Authors | Hara, K.,Chen, Z.,Tomchick, D.R.,Yu, H. (deposition date: 2014-05-12, release date: 2014-08-27, Last modification date: 2023-11-15) |
Primary citation | Hara, K.,Zheng, G.,Qu, Q.,Liu, H.,Ouyang, Z.,Chen, Z.,Tomchick, D.R.,Yu, H. Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat.Struct.Mol.Biol., 21:864-870, 2014 Cited by PubMed: 25173175DOI: 10.1038/nsmb.2880 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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