4PF5
Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain
Summary for 4PF5
Entry DOI | 10.2210/pdb4pf5/pdb |
Descriptor | Concanavalin-A, MANGANESE (II) ION, 4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole, ... (5 entities in total) |
Functional Keywords | sugar binding protein, lectin, high mannose |
Biological source | Canavalia ensiformis (Jack bean) |
Total number of polymer chains | 2 |
Total formula weight | 52111.12 |
Authors | Lafite, P.,Daniellou, R. (deposition date: 2014-04-28, release date: 2014-12-17, Last modification date: 2024-05-08) |
Primary citation | Francois-Heude, M.,Mendez-Ardoy, A.,Cendret, V.,Lafite, P.,Daniellou, R.,Ortiz Mellet, C.,Garcia Fernandez, J.M.,Moreau, V.,Djedaini-Pilard, F. Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins? Chemistry, 21:1978-1991, 2015 Cited by PubMed: 25483029DOI: 10.1002/chem.201405481 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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