4PD4

Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action

4PD4 の概要

• エントリーDOI: 10.2210/pdb4pd4/pdb
• 分子名称: Cytochrome b-c1 complex subunit 1, mitochondrial, Igh protein, Ig kappa chain V-V region HP 124E1, ... (18 entities in total)
• 機能のキーワード: cytochrome bc1 complex, membrane protein complex, antimalarial drug, inhibitor, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 11
• 化学式量合計: 251150.07

構造登録者

Birth, D.,Kao, W.-C.,Hunte, C. (登録日: 2014-04-17, 公開日: 2014-06-11, 最終更新日: 2023-12-27)

• 主引用文献: Birth, D.,Kao, W.C.,Hunte, C.; Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action.; Nat Commun, 5:4029-4029, 2014; PubMed: 24893593; DOI: 10.1038/ncomms5029

実験手法

X-RAY DIFFRACTION (3.04 Å)