4PCW
Crystal Structure of the N-terminal Domain of Human Profilaggrin at 2.2 A Resolution
Summary for 4PCW
Entry DOI | 10.2210/pdb4pcw/pdb |
Descriptor | Filaggrin, CALCIUM ION, NONAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | s100 protein, ef-hand calcium binding protein, epidermal skin protein, signaling protein, metal binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasmic granule : P20930 |
Total number of polymer chains | 4 |
Total formula weight | 45993.19 |
Authors | Bunick, C.G.,Steitz, T.A. (deposition date: 2014-04-16, release date: 2015-04-01, Last modification date: 2023-09-27) |
Primary citation | Bunick, C.G.,Presland, R.B.,Lawrence, O.T.,Pearton, D.J.,Milstone, L.M.,Steitz, T.A. Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27. J. Invest. Dermatol., 135:1801-1809, 2015 Cited by PubMed: 25760235DOI: 10.1038/jid.2015.102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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