4P7U

Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with NDSB-201

Summary for 4P7U

• Entry DOI: 10.2210/pdb4p7u/pdb
• Related: 1M9Z 1PLO 4XJJ
• Descriptor: TGF-beta receptor type-2, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE (3 entities in total)
• Functional Keywords: ndsb-201, type ii transforming growth factor beta receptor, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 12956.68

Authors

Wangkanont, K.,Forest, K.T. (deposition date: 2014-03-27, release date: 2015-06-24, Last modification date: 2023-09-27)

• Primary citation: Wangkanont, K.,Forest, K.T.,Kiessling, L.L.; The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-beta receptor extracellular domain.; Protein Expr.Purif., 115:19-25, 2015; PubMed: 26073093; DOI: 10.1016/j.pep.2015.06.001

Experimental method

X-RAY DIFFRACTION (1.502 Å)