4P7F

Mouse apo-COMT

4P7F の概要

• エントリーDOI: 10.2210/pdb4p7f/pdb
• 関連するPDBエントリー: 4P7G 4P7J 4P7K
• 分子名称: Catechol O-methyltransferase, SODIUM ION, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: methyltransferase, neurotransmitter degradation, transferase, alternative initiation, catecholamine metabolism, cell membrane, metal-binding, phosphoprotein, s-adenosyl-l-methionine, signal-anchor, transmembrane anchor, enzyme mechanism, conformational change
• 由来する生物種: Mus musculus (Mouse)
• 細胞内の位置: Isoform Soluble: Cytoplasm. Isoform Membrane-bound: Cell membrane; Single-pass type II membrane protein; Extracellular side: O88587
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25339.29

構造登録者

Ehler, A.,Benz, J.,Schlatter, D.,Rudolph, M.G. (登録日: 2014-03-27, 公開日: 2014-06-11, 最終更新日: 2023-12-27)

• 主引用文献: Ehler, A.,Benz, J.,Schlatter, D.,Rudolph, M.G.; Mapping the conformational space accessible to catechol-O-methyltransferase.; Acta Crystallogr.,Sect.D, 70:2163-2174, 2014; PubMed: 25084335; DOI: 10.1107/S1399004714012917

実験手法

X-RAY DIFFRACTION (1.37 Å)