4P39
Crystal structure of the human C5aR antagonist C5a-A8
Summary for 4P39
| Entry DOI | 10.2210/pdb4p39/pdb |
| Related | 3HQA 3HQB 4P3A 4P3B |
| Descriptor | Complement C5 (2 entities in total) |
| Functional Keywords | complement anaphylatoxin, c5a, three-helix bundle, gpcr antagonist, immune system |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted: P01031 |
| Total number of polymer chains | 4 |
| Total formula weight | 33462.71 |
| Authors | Yatime, L.,Schatz-Jakobsen, J.A.,Larsen, C.,Andersen, G.R. (deposition date: 2014-03-06, release date: 2014-06-11, Last modification date: 2023-09-27) |
| Primary citation | Schatz-Jakobsen, J.A.,Yatime, L.,Larsen, C.,Petersen, S.V.,Klos, A.,Andersen, G.R. Structural and functional characterization of human and murine C5a anaphylatoxins. Acta Crystallogr. D Biol. Crystallogr., 70:1704-1717, 2014 Cited by PubMed: 24914981DOI: 10.1107/S139900471400844X PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.401 Å) |
Structure validation
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