4OV8

Crystal Structure of the TMH1-lock mutant of the mature form of pleurotolysin B

4OV8 の概要

• エントリーDOI: 10.2210/pdb4ov8/pdb
• 分子名称: Pleurotolysin B, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: tmh1-lock, macpf domain, pore-forming protein, pleurtolysin a component, toxin
• 由来する生物種: Pleurotus ostreatus (Oyster mushroom)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52656.41

構造登録者

Kondos, S.C.,Law, R.H.P.,Whisstock, J.C.,Dunstone, M.A. (登録日: 2014-02-20, 公開日: 2015-02-18, 最終更新日: 2023-11-08)

• 主引用文献: Lukoyanova, N.,Kondos, S.C.,Farabella, I.,Law, R.H.P.,Reboul, C.F.,Caradoc-Davies, T.T.,Spicer, B.A.,Kleifeld, O.,Traore, D.A.,Ekkel, S.M.,Voskoboinik, I.,Trapani, J.A.,Hatfaludi, T.,Oliver, K.,Hotze, E.M.,Tweten, R.K.,Whisstock, J.C.,Topf, M.,Saibil, H.R.,Dunstone, M.A.; Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin; Plos Biol., 13:e1002049-e1002049, 2015; PubMed: 25654333; DOI: 10.1371/journal.pbio.1002049

実験手法

X-RAY DIFFRACTION (2.15 Å)