4OT9
crystal structure of the C-terminal domain of p100/NF-kB2
Summary for 4OT9
Entry DOI | 10.2210/pdb4ot9/pdb |
Descriptor | Nuclear factor NF-kappa-B p100 subunit, SULFATE ION (2 entities in total) |
Functional Keywords | nf-kb transcription factor, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q00653 |
Total number of polymer chains | 1 |
Total formula weight | 38474.31 |
Authors | Tao, Z.H.,Huang, D.B.,Fusco, A.,Gupta, K.,Ware, C.F.,Duynne, G.V. (deposition date: 2014-02-13, release date: 2015-01-14, Last modification date: 2024-02-28) |
Primary citation | Tao, Z.,Fusco, A.,Huang, D.B.,Gupta, K.,Young Kim, D.,Ware, C.F.,Van Duyne, G.D.,Ghosh, G. p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation. Proc.Natl.Acad.Sci.USA, 111:15946-15951, 2014 Cited by PubMed: 25349408DOI: 10.1073/pnas.1408552111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.35 Å) |
Structure validation
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