4OSO
The crystal structure of landomycin C-6 ketoreductase LanV with bound NADP and rabelomycin
Summary for 4OSO
Entry DOI | 10.2210/pdb4oso/pdb |
Related | 4KWH 4KWI 4OSP |
Descriptor | Reductase homolog, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, rabelomycin, ... (5 entities in total) |
Functional Keywords | rossmann fold, ketoreductase, nadph binding, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic |
Biological source | Streptomyces cyanogenus |
Total number of polymer chains | 2 |
Total formula weight | 57377.82 |
Authors | Paananen, P.,Niiranen, L.,Patrikainen, P.,Metsa-Ketela, M. (deposition date: 2014-02-13, release date: 2014-10-01, Last modification date: 2023-09-20) |
Primary citation | Patrikainen, P.,Niiranen, L.,Thapa, K.,Paananen, P.,Tahtinen, P.,Mantsala, P.,Niemi, J.,Metsa-Ketela, M. Structure-based engineering of angucyclinone 6-ketoreductases. Chem.Biol., 21:1381-1391, 2014 Cited by PubMed: 25200607DOI: 10.1016/j.chembiol.2014.07.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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