4ORB

Crystal structure of mouse calcineurin

Summary for 4ORB

Related4OR9 4ORA 4ORC
DescriptorSerine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ZINC ION, ... (6 entities in total)
Functional Keywordscalmodulin-binding, hydrolase-metal binding protein complex, hydrolase/metal binding protein
Biological sourceMus musculus (mouse)
Cellular locationCell membrane P63328
Cytoplasm, cytosol  Q63810
Total number of polymer chains2
Total molecular weight78359.2
Authors
Ma, L.,Li, S.J.,Wang, J.,Wu, J.W.,Wang, Z.X. (deposition date: 2014-02-11, release date: 2015-05-20, Last modification date: 2016-12-21)
Primary citation
Li, S.J.,Ma, L.,Wang, J.,Lu, C.,Wang, J.,Wu, J.W.,Wang, Z.X.
Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published,
Experimental method
X-RAY DIFFRACTION (3.108 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2371103.7%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution