4OQT

LINGO-1/Li81 Fab complex

Summary for 4OQT

• Entry DOI: 10.2210/pdb4oqt/pdb
• Descriptor: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Light Chain of Li81 Fab, kappa 3, Heavy Chain of Li81 Fab, VH3-23, ... (6 entities in total)
• Functional Keywords: leucine rich repeat, ig domain, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 105886.24

Authors

Pepinsky, R.B.,Arndt, J.W.,Quan, C.,Gao, Y.,Quintero-Monzon, O.,Lee, X.,Mi, S. (deposition date: 2014-02-10, release date: 2014-05-14, Last modification date: 2020-07-29)

• Primary citation: Pepinsky, R.B.,Arndt, J.W.,Quan, C.,Gao, Y.,Quintero-Monzon, O.,Lee, X.,Mi, S.; Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy.; J.Pharmacol.Exp.Ther., 350:110-123, 2014; PubMed: 24756303; DOI: 10.1124/jpet.113.211771

Experimental method

X-RAY DIFFRACTION (3.23 Å)