4OQM

Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU

4OQM の概要

• エントリーDOI: 10.2210/pdb4oqm/pdb
• 関連するPDBエントリー: 4OQL 4OQN 4OQX
• 分子名称: Thymidine kinase, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethynylpyrimidine-2,4(1H,3H)-dione, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: dna synthesis, thymidine kinase, atp-binding, nucleotide-binding, transferase, 5-ethynyluridine nucleoside derivative
• 由来する生物種: Human herpesvirus 1 (HHV-1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72933.34

構造登録者

Pernot, L.,Neef, A.B.,Westermaier, Y.,Perozzo, R.,Luedtke, N.,Scapozza, L. (登録日: 2014-02-10, 公開日: 2014-08-13, 最終更新日: 2023-09-20)

• 主引用文献: Pernot, L.,Neef, A.B.,Westermaier, Y.,Perozzo, R.,Luedtke, N.,Scapozza, L.; Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU; To be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)