4OO6

Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)

Summary for 4OO6

• Entry DOI: 10.2210/pdb4oo6/pdb
• Related: 4JLQ
• Descriptor: Transportin-1, RNA-binding protein 39 (3 entities in total)
• Functional Keywords: karyopherin, trnaportin, importin, heat repeats, nuclear import, protein transport, nls, nuclear localization signal, rna-binding protein, hcc1, nucleocytoplasmic transport: a target for cellular control (npcxstals), new york structural genomics research consortium (nysgrc), psi-biology, transport protein-rna binding protein complex, npcxstals, transport protein/rna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q92973; Nucleus speckle: Q14498
• Total number of polymer chains: 2
• Total formula weight: 100351.84

Authors

Sampathkumar, P.,Brower, A.,Soniat, M.,Bonanno, J.,Hillerich, B.,Seidel, R.D.,Rout, M.P.,Chook, Y.M.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC),Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) (deposition date: 2014-01-30, release date: 2014-02-12, Last modification date: 2023-09-20)

• Primary citation: Sampathkumar, P.,Brower, A.,Soniat, M.,Bonanno, J.,Hillerich, B.,Seidel, R.D.,Rout, M.P.,Chook, Y.M.,Almo, S.C.; Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1); to be published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)