4OND
Ancestral Steroid Receptor 2 DBD helix mutant - ERE DNA complex
Summary for 4OND
Entry DOI | 10.2210/pdb4ond/pdb |
Related | 4OLN 4OOR |
Descriptor | Ancestral SR2 Helix Mutant, 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*G)-3', ... (5 entities in total) |
Functional Keywords | nuclear receptor dna binding domain, zinc finger, transcription factor, coregulators, transcription-dna complex, transcription/dna |
Biological source | synthetic construct |
Total number of polymer chains | 8 |
Total formula weight | 58744.63 |
Authors | Ortlund, E.O.,Murphy, M.N. (deposition date: 2014-01-28, release date: 2014-10-29, Last modification date: 2024-02-28) |
Primary citation | McKeown, A.N.,Bridgham, J.T.,Anderson, D.W.,Murphy, M.N.,Ortlund, E.A.,Thornton, J.W. Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell(Cambridge,Mass.), 159:58-68, 2014 Cited by PubMed: 25259920DOI: 10.1016/j.cell.2014.09.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.253 Å) |
Structure validation
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