4ONC
Crystal Structure of Mycobacterium Tuberculosis Decaprenyl Diphosphate Synthase in Complex with BPH-640
Summary for 4ONC
| Entry DOI | 10.2210/pdb4onc/pdb |
| Descriptor | Decaprenyl diphosphate synthase, [hydroxy(1,1':3',1''-terphenyl-3-yl)methanediyl]bis(phosphonic acid) (3 entities in total) |
| Functional Keywords | polyprenyl transferase, decaprenyl diphosphate synthase, transferase |
| Biological source | Mycobacterium tuberculosis |
| Cellular location | Cell membrane: P60479 |
| Total number of polymer chains | 2 |
| Total formula weight | 65762.20 |
| Authors | Feng, X.,Chan, H.C.,Ko, T.P. (deposition date: 2014-01-28, release date: 2014-04-02, Last modification date: 2023-11-08) |
| Primary citation | Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T. Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis J.Am.Chem.Soc., 136:2892-2896, 2014 Cited by PubMed: 24475925DOI: 10.1021/ja413127v PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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