4ONC

Crystal Structure of Mycobacterium Tuberculosis Decaprenyl Diphosphate Synthase in Complex with BPH-640

4ONC の概要

• エントリーDOI: 10.2210/pdb4onc/pdb
• 分子名称: Decaprenyl diphosphate synthase, [hydroxy(1,1':3',1''-terphenyl-3-yl)methanediyl]bis(phosphonic acid) (3 entities in total)
• 機能のキーワード: polyprenyl transferase, decaprenyl diphosphate synthase, transferase
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cell membrane: P60479
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65762.20

構造登録者

Feng, X.,Chan, H.C.,Ko, T.P. (登録日: 2014-01-28, 公開日: 2014-04-02, 最終更新日: 2023-11-08)

• 主引用文献: Chan, H.C.,Feng, X.,Ko, T.P.,Huang, C.H.,Hu, Y.,Zheng, Y.,Bogue, S.,Nakano, C.,Hoshino, T.,Zhang, L.,Lv, P.,Liu, W.,Crick, D.C.,Liang, P.H.,Wang, A.H.,Oldfield, E.,Guo, R.T.; Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis; J.Am.Chem.Soc., 136:2892-2896, 2014; PubMed: 24475925; DOI: 10.1021/ja413127v

実験手法

X-RAY DIFFRACTION (1.83 Å)