4OME

X-ray structure of human glutamate carboxypeptidase II in complex with DCCBL, a urea based inhibitor with distal carborane moiety

4OME の概要

• エントリーDOI: 10.2210/pdb4ome/pdb
• 分子名称: Glutamate carboxypeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: hydrolase, metallopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Single-pass type II membrane protein . Isoform PSMA': Cytoplasm: Q04609
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 83158.28

構造登録者

Barinka, C.,Ptacek, J.,Novakova, Z.,Byun, Y. (登録日: 2014-01-27, 公開日: 2015-02-18, 最終更新日: 2020-07-29)

• 主引用文献: Barinka, C.,Ptacek, J.,Novakova, Z.,Byun, Y.; X-ray structure of human glutamate carboxypeptidase II in complex with DCCBL, a urea based inhibitor with distal carborane moiety; To be Published,

実験手法

X-RAY DIFFRACTION (1.79 Å)